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Temporal variation of PM-associated health effects in Shijiazhuang, Hebei

《环境科学与工程前沿（英文）》 2021年 第15卷 第5期 doi: 10.1007/s11783-020-1376-0

摘要：

•Annual mean PM2.5 in Shijiazhuang were 87, 95, and 82 µg/m3 in 2015–2017.

关键词： PM2.5     Health effects     Integrated exposure-response model     Shijiazhuang    

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Exposure-response of Cr(III)-organic complexes to Saccharomyces cerevisiae

Nivedita CHATTERJEE, Zejiao LUO,

《环境科学与工程前沿（英文）》 2010年 第4卷 第2期   页码 196-202 doi: 10.1007/s11783-010-0008-5

摘要： Hexavalent chromium [Cr(VI)] bioreduction produces soluble Cr(III)-organic complexes. The Cr(III)-organic complexes are relatively stable once they are formed, and no data about their toxicity were reported. Therefore, this study aims to investigate the bioavailability and toxicity of the soluble Cr(III)-organic complexes. L-1 wild type yeast strain was chosen as the model organism and Cr(III)-citrate was selected as the representative compound of the Cr(III)-organic complexes. The short-term chronic aquatic toxicity tests of the Cr(III)-citrate was explored by measuring growth inhibition, direct viable cell count, dry biomass, biosorption, and the amount of CO production. Cr(III)-citrate exerted a toxicity of 51mg/L with an , which was calculated from the percent growth inhibition. These toxicity data would be helpful to define the toxic potential of the organo-chromium-III compounds in the environment.

关键词： Cr(III)-organic complexes     Saccharomyces cerevisiae     toxicity     EC50     bioavailability    

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Universal influenza virus vaccines: what can we learn from the human immune response following exposure

null

《医学前沿（英文）》 2017年 第11卷 第4期   页码 471-479 doi: 10.1007/s11684-017-0602-z

摘要：

Several universal influenza virus vaccine candidates based on eliciting antibodies against the hemagglutinin stalk domain are in development. Typically, these vaccines induce responses that target group 1 or group 2 hemagglutinins with little to no cross-group reactivity and protection. Similarly, the majority of human anti-stalk monoclonal antibodies that have been isolated are directed against group 1 or group 2 hemagglutinins with very few that bind to hemagglutinins of both groups. Here we review what is known about the human humoral immune response to vaccination and infection with H7 subtype influenza viruses on a polyclonal and monoclonal level. It seems that unlike vaccination with H5 hemagglutinin, which induces antibody responses mostly restricted to the group 1 stalk domain, H7 exposure induces both group 2 and cross-group antibody responses. A better understanding of this phenomenon and the underlying mechanisms might help to develop future universal influenza virus vaccine candidates.

关键词： universal influenza virus vaccine     hemagglutinin stalk     H7N9    

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Long-term exposure to air pollution and cerebrovascular disease: findings from Beijing Health Management

《环境科学与工程前沿（英文）》 2023年 第17卷 第7期 doi: 10.1007/s11783-023-1684-2

摘要：

● This study explored the long-term association by double robust additive models.

关键词： Air pollution     Cerebrovascular disease     Incidence     Long-term exposure     Doubly robust additive model    

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Response of bacterial communities to short-term pyrene exposure in red soil

Jingjing PENG, Hong LI, Jianqiang SU, Qiufang ZHANG, Junpeng RUI, Chao CAI

《环境科学与工程前沿（英文）》 2013年 第7卷 第4期   页码 559-567 doi: 10.1007/s11783-013-0501-8

摘要： Pyrene, a representative polycyclic aromatic hydrocarbon (PAH) compound produced mainly from incomplete combustion of fossil fuels, is hazardous to ecosystem health. However, long-term exposure studies did not detect any significant effects of pyrene on soil microorganism. In this study, short-term microcosm experiments were conducted to identify the immediate effect of pyrene on soil bacterial communities. A freshly-collected pristine red soil was spiked with pyrene at 0, 10, 100, 200, and 500 mg·kg and incubated for one day and seven days. The bacterial communities in the incubated soils were analyzed using 16S rRNA sequencing and terminal restriction fragment length polymorphism (T-RFLP) methods. The results revealed high bacterial diversity in both unspiked and pyrene-spiked soils. Only at the highest pyrene-spiking rate of 500 mg·kg , two minor bacteria groups of the identified 14 most abundant bacteria groups were completely suppressed. Short-term exposure to pyrene resulted in dominance of Proteobacteria in soil, followed by Acidobacteria, Firmutes, and Bacteroidetes. Our findings showed that bacterial community structure did respond to the presence of pyrene but recovered rapidly from the perturbation. The intensity of impact and the rate of recovery showed some pyrene dosage-dependent trends. Our results revealed that different levels of pyrene may affect the bacterial community structure by suppressing or selecting certain groups of bacteria. It was also found that the bacterial community was most susceptible to pyrene within one day of the chemical addition.

关键词： pyrene     bacterial communities     terminal restriction fragment length polymorphism     short-term exposure     rank-abundance plots    

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Purification and concentration of gluconic acid from an integrated fermentation and membrane processusing response surface optimized conditions

Parimal Pal, Ramesh Kumar, Subhamay Banerjee

《化学科学与工程前沿（英文）》 2019年 第13卷 第1期   页码 152-163 doi: 10.1007/s11705-018-1721-z

摘要： A response surface method was used to optimize the purification and concentration of gluconic acid from fermentation broth using an integrated membrane system. was used for the bioconversion of the glucose in sugarcane juice to gluconic acid (concentration 45 g?L ) with a yield of 0.9 g?g . The optimum operating conditions, such as trans-membrane pressure (TMP), pH, cross-flow rate (CFR) and initial gluconic acid concentration, were determined using response surface methodology. Five different types of polyamide nanofiltration membranes were screened and the best performing one was then used for downstream purification of gluconic acid in a flat sheet cross-flow membrane module. Under the optimum conditions (TMP= 12 bar and CFR= 400 L?h ), this membrane retained more than 85% of the unconverted glucose from the fermentation broth and had a gluconic acid permeation rate of 88% with a flux of 161 L?m ?h . Using response surface methods to optimize this green nanofiltration process is an effective way of controlling the production of gluconic acid so that an efficient separation with high flux is obtained.

关键词： gluconic acid     optimized nanofiltration     green processing     process intensification    

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Integrated analysis of gut microbiome and host immune responses in COVID-19

《医学前沿（英文）》 2022年 第16卷 第2期   页码 263-275 doi: 10.1007/s11684-022-0921-6

摘要： Emerging evidence indicates that the gut microbiome contributes to the host immune response to infectious diseases. Here, to explore the role of the gut microbiome in the host immune responses in COVID-19, we conducted shotgun metagenomic sequencing and immune profiling of 14 severe/critical and 24 mild/moderate COVID-19 cases as well as 31 healthy control samples. We found that the diversity of the gut microbiome was reduced in severe/critical COVID-19 cases compared to mild/moderate ones. We identified the abundance of some gut microbes altered post-SARS-CoV-2 infection and related to disease severity, such as Enterococcus faecium, Coprococcus comes, Roseburia intestinalis, Akkermansia muciniphila, Bacteroides cellulosilyticus and Blautia obeum. We further analyzed the correlation between the abundance of gut microbes and host responses, and obtained a correlation map between clinical features of COVID-19 and 16 severity-related gut microbe, including Coprococcus comes that was positively correlated with CD3+/CD4+/CD8+ lymphocyte counts. In addition, an integrative analysis of gut microbiome and the transcriptome of peripheral blood mononuclear cells (PBMCs) showed that genes related to viral transcription and apoptosis were up-regulated in Coprococcus comes low samples. Moreover, a number of metabolic pathways in gut microbes were also found to be differentially enriched in severe/critical or mild/moderate COVID-19 cases, including the superpathways of polyamine biosynthesis II and sulfur oxidation that were suppressed in severe/critical COVID-19. Together, our study highlighted a potential regulatory role of severity related gut microbes in the immune response of host.

关键词： COVID-19     SARS-COV-2     gut microbiome     immune response    

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Relations between indoor and outdoor PM

Cong Liu, Yinping Zhang

《环境科学与工程前沿（英文）》 2019年 第13卷 第1期 doi: 10.1007/s11783-019-1089-4

摘要：

Factors impacting indoor-outdoor relations are introduced.

Sulfate seems a fine tracer for other non-volatile species.

Particulate nitrate and ammonium desorb during outdoor-to-indoor transport.

OC load increases during the transport due to sorption of indoor SVOCs.

关键词： Indoor air quality     Exposure     SVOC     Reactive oxidative species     Oxidative potential     Chemical transport model    

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Integrated transmission and generation planning model in a deregulated environment

Enrique B. CEDE?O, Sant ARORA

《能源前沿（英文）》 2013年 第7卷 第2期   页码 182-190 doi: 10.1007/s11708-013-0256-8

摘要： After the deregulation of the Power Sector in the U.S., planning for generation and transmission capacities is decentralized. There is, however, still need for the long term integrated planning of generation and transmission capacities at the macro level, since these two sectors must operate in a coordinated manner. This paper presents a model for integrating generation and transmission expansion planning to identify an indicative expansion plan for the total sector at the macro level. The argument for an integrated model is supported using evidence from integrated planning efforts in real life systems. The application of the proposed model is illustrated using an example that requires expansion of generation and transmission capacities over three regions in a deregulated power system. The example considers that addition of generating capacity should come from renewable sources. The test results show the potential cost saving from integrated planning.

关键词： integrated planning     indicative plans     power generation     transmission     deregulation    

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Comparison and harmonization of building wind loading codes among the Asia-Pacific Economies

Yaojun GE, Shuyang CAO, Xinyang JIN

《结构与土木工程前沿（英文）》 2013年 第7卷 第4期   页码 402-410 doi: 10.1007/s11709-013-0230-x

摘要： This paper reviews wind loading codes and standards in the Asia-Pacific Region, in particular in the 15 countries and areas. A general description of wind loading model is given as a famous wind loading chain described by four variables including velocity pressure, exposure factor, pressure coefficient, and gust response factor. Through the APEC-WW Workshops and the extensive calculations for three examples of low, medium and high rise buildings, these four important variables of wind loads are evaluated and compared with statistical parameters, mean values and coefficients of variation. The main results of the comparison show some differences among the 15 economies, and the reasons and further incorporation are discussed and suggested.

关键词： wind loading     codification     velocity pressure     exposure factor     pressure coefficient     gust response factor    

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An operating state estimation model for integrated energy systems based on distributed solution

Dengji ZHOU, Shixi MA, Dawen HUANG, Huisheng ZHANG, Shilie WENG

《能源前沿（英文）》 2020年 第14卷 第4期   页码 801-816 doi: 10.1007/s11708-020-0687-y

摘要： In view of the disadvantages of the traditional energy supply systems, such as separate planning, separate design, independent operating mode, and the increasingly prominent nonlinear coupling between various sub-systems, the production, transmission, storage and consumption of multiple energy sources are coordinated and optimized by the integrated energy system, which improves energy and infrastructure utilization, promotes renewable energy consumption, and ensures reliability of energy supply. In this paper, the mathematical model of the electricity-gas interconnected integrated energy system and its state estimation method are studied. First, considering the nonlinearity between measurement equations and state variables, a performance simulation model is proposed. Then, the state consistency equations and constraints of the coupling nodes for multiple energy sub-systems are established, and constraints are relaxed into the objective function to decouple the integrated energy system. Finally, a distributed state estimation framework is formed by combining the synchronous alternating direction multiplier method to achieve an efficient estimation of the state of the integrated energy system. A simulation model of an electricity-gas interconnected integrated energy system verifies the efficiency and accuracy of the state estimation method proposed in this paper. The results show that the average relative errors of voltage amplitude and node pressure estimated by the proposed distributed state estimation method are only 0.0132% and 0.0864%, much lower than the estimation error by using the Lagrangian relaxation method. Besides, compared with the centralized estimation method, the proposed distributed method saves 5.42 s of computation time. The proposed method is more accurate and efficient in energy allocation and utilization.

关键词： integrated energy system     state estimation     electricity-gas coupling energy system     nonlinear coupling     distributed solution    

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An integrated model for structure optimization and technology screening of urban wastewater systems

Yue HUANG,Xin DONG,Siyu ZENG,Jining CHEN

《环境科学与工程前沿（英文）》 2015年 第9卷 第6期   页码 1036-1048 doi: 10.1007/s11783-015-0792-z

摘要： The conventional approach to wastewater system design and planning considers each component separately and does not provide the optimum performance of the entire system. However, the growing concern for environmental protection, economic efficiency, and sustainability of urban wastewater systems requires an integrated modeling of subsystems and a synthetic evaluation of multiple objectives. In this study, a multi-objective optimization model of an integrated urban wastewater system was developed. The model encompasses subsystems, such as a sewer system, stormwater management, municipal wastewater treatment, and a wastewater reclamation system. The non-dominated sorting genetic algorithm (NSGA-II) was used to generate a range of system design possibilities to optimize conflicting environmental and economic objectives. Information from a knowledge base, which included rules for generating treatment trains as well as the performance characteristics of commonly used water pollution control measures, was utilized. The trade-off relationships between the objectives, total water pollution loads to the environment, and life cycle costs (which consist of investment as well as operation and maintenance costs), can be illustrated using Pareto charts. The developed model can be used to assist decision makers in the preliminary planning of system structure. A benchmark city was constructed to illustrate the methods of multi-objective controls, highlight cost-effective water pollution control measures, and identify the main pressures on urban water environment.

关键词： urban wastewater system     integrated modeling     multi-objective optimization     non-dominated sorting genetic algorithm (NSGA-II)    

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Development and application of a random walk model of atmospheric diffusion in the emergency response

CHI Bing, LI Hong, FANG Dong

《能源前沿（英文）》 2007年 第1卷 第2期   页码 195-201 doi: 10.1007/s11708-007-0025-7

摘要： Plume concentration prediction is one of the main contents of radioactive consequence assessment for early emergency response to nuclear accidents. Random characteristics of atmospheric diffusion itself was described, a random walk model of atmospheric diffusion (Random Walk) was introduced and compared with the Lagrangian puff model (RIMPUFF) in the nuclear emergency decision support system (RODOS) developed by the European Community for verification. The results show the concentrations calculated by the two models are quite close except that the plume area calculated by Random Walk is a little smaller than that by RIMPUFF. The random walk model for atmospheric diffusion can simulate the atmospheric diffusion in case of nuclear accidents, and provide more actual information for early emergency and consequence assessment as one of the atmospheric diffusion module of the nuclear emergency decision support system.

关键词： RODOS     concentration prediction     information     nuclear     RIMPUFF    

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A fuzzy model for assessing the risk exposure of procuring infrastructure mega-projects through public-private

Albert P.C. CHAN, Robert OSEI-KYEI, Yi HU, Yun LE

《工程管理前沿（英文）》 2018年 第5卷 第1期   页码 64-77 doi: 10.15302/J-FEM-2018067

摘要： Considering the rapid urbanization growth rate particularly in developing countries, the number of infrastructure mega-projects over the past years has risen tremendously. Essentially, because infrastructure mega-projects require huge investment funds, better management skills, well qualified and experienced international expertise and technology innovation, they are mostly preferred to be procured using the PPP method compare to the use of the traditional bid-build system. In this regard, this paper aims to develop a fuzzy evaluation model for assessing the suitability of procuring infrastructure mega-projects through PPP by considering their risk exposure. The main body of Hong Kong-Zhuhai-Macao Bridge (HZMB) is used as a case project to demonstrate the practicality of the risk evaluation model. The risk evaluation model consists of four critical risk groupings, these include, construction and land risks, commercial risks, operational risks and political risks. Using the risk evaluation equation, a risk index of 4.53 out of 5.00 is computed for the selected project if it is procured through the PPP scheme. This outcome shows that the case project is not suitable for the PPP approach because its risk exposure is very high. The model developed will enable PPP practitioners to predict the likely risk exposure of procuring infrastructure mega-projects through the PPP scheme.

关键词： infrastructure mega-projects     public-private partnership     Hong Kong-Zhuhai-Macao Bridge     Hong Kong     fuzzy    

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Enhancement of the polynomial functions response surface model for real-time analyzing ozone sensitivity

Jiangbo Jin, Yun Zhu, Jicheng Jang, Shuxiao Wang, Jia Xing, Pen-Chi Chiang, Shaojia Fan, Shicheng Long

《环境科学与工程前沿（英文）》 2021年 第15卷 第2期 doi: 10.1007/s11783-020-1323-0

摘要： Abstract • The calculation process and algorithm of response surface model (RSM) were enhanced. • The prediction errors of RSM in the margin and transition areas were greatly reduced. • The enhanced RSM was able to analyze O3-NOx-VOC sensitivity in real-time. • The O3 formations were mainly sensitive to VOC, for the two case study regions. Quantification of the nonlinearities between ambient ozone (O3) and the emissions of nitrogen oxides (NOx) and volatile organic compound (VOC) is a prerequisite for an effective O3 control strategy. An Enhanced polynomial functions Response Surface Model (Epf-RSM) with the capability to analyze O3-NOx-VOC sensitivities in real time was developed by integrating the hill-climbing adaptive method into the optimized Extended Response Surface Model (ERSM) system. The Epf-RSM could single out the best suited polynomial function for each grid cell to quantify the responses of O3 concentrations to precursor emission changes. Several comparisons between Epf-RSM and pf-ERSM (polynomial functions based ERSM) were performed using out-of-sample validation, together with comparisons of the spatial distribution and the Empirical Kinetic Modeling Approach diagrams. The comparison results showed that Epf-RSM effectively addressed the drawbacks of pf-ERSM with respect to over-fitting in the margin areas and high biases in the transition areas. The O3 concentrations predicted by Epf-RSM agreed well with Community Multi-scale Air Quality simulation results. The case study results in the Pearl River Delta and the north-western area of the Shandong province indicated that the O3 formations in the central areas of both the regions were more sensitive to anthropogenic VOC in January, April, and October, while more NOx-sensitive in July.

关键词： Response surface model     Hill-climbing algorithm     Ozone pollution     Precursor emissions     Control strategy    

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标题 作者 时间 类型 操作

Temporal variation of PM-associated health effects in Shijiazhuang, Hebei

期刊论文

Exposure-response of Cr(III)-organic complexes to Saccharomyces cerevisiae

Nivedita CHATTERJEE, Zejiao LUO,

期刊论文

Universal influenza virus vaccines: what can we learn from the human immune response following exposure

null

期刊论文

Long-term exposure to air pollution and cerebrovascular disease: findings from Beijing Health Management

期刊论文

Response of bacterial communities to short-term pyrene exposure in red soil

Jingjing PENG, Hong LI, Jianqiang SU, Qiufang ZHANG, Junpeng RUI, Chao CAI

期刊论文

Purification and concentration of gluconic acid from an integrated fermentation and membrane processusing response surface optimized conditions

Parimal Pal, Ramesh Kumar, Subhamay Banerjee

期刊论文

Integrated analysis of gut microbiome and host immune responses in COVID-19

期刊论文

Relations between indoor and outdoor PM

Cong Liu, Yinping Zhang

期刊论文

Integrated transmission and generation planning model in a deregulated environment

Enrique B. CEDE?O, Sant ARORA

期刊论文

Comparison and harmonization of building wind loading codes among the Asia-Pacific Economies

Yaojun GE, Shuyang CAO, Xinyang JIN

期刊论文

An operating state estimation model for integrated energy systems based on distributed solution

Dengji ZHOU, Shixi MA, Dawen HUANG, Huisheng ZHANG, Shilie WENG

期刊论文

An integrated model for structure optimization and technology screening of urban wastewater systems

Yue HUANG,Xin DONG,Siyu ZENG,Jining CHEN

期刊论文

Development and application of a random walk model of atmospheric diffusion in the emergency response

CHI Bing, LI Hong, FANG Dong

期刊论文

A fuzzy model for assessing the risk exposure of procuring infrastructure mega-projects through public-private

Albert P.C. CHAN, Robert OSEI-KYEI, Yi HU, Yun LE

期刊论文

Enhancement of the polynomial functions response surface model for real-time analyzing ozone sensitivity

Jiangbo Jin, Yun Zhu, Jicheng Jang, Shuxiao Wang, Jia Xing, Pen-Chi Chiang, Shaojia Fan, Shicheng Long

期刊论文